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Mitotropin from Gaspari Nutrition is not another "HARDCORE" or "EXTREME" fat burner destined to only burn a hole in your pocket. Let's face it, fat burners are long dead because the category hasn't delivered the results you've been after in years. It's time for a new class of compounds with unrivaled power that can deliver a total reconfiguration of your body's composition in just a single box.
Try Mitotropin today and detonate this incredible neutron bomb of a product on your own physique. From the only company with the fire power to deliver it -Gaspari Nutrition.
Mitoropin - Uncoupling Complex
Mitochondria are the cellular powerhouses responsible for providing energy for physical activity. However, when it comes to fat loss, they have a great potential to transform into a fat burning inferno provided the right set of clinically research ingredients provide the substrates to do so. One extremely effective way to do this is by increasing anion carrier proteins more commonly known as uncoupling proteins (UCP's). These are found within all mammals but can decrease as metabolic rate slows and age progresses. Fortunately, if you increase their presence within the mitochondria metabolic rate is increased and as a result, fat can begin to melt away. One of the primary ingredients involved in this process is natural seaweed extract called fucoxanthin. It has shown to increase UCP-1 in white adipose tissue which can lead to increased metabolic rate and reduction in visceral fat deposits such as those found in the belly/gut region. Combined with 3,3'diiodothyronine and 3,5 diidothyronine the expression of the carnitine palmitoyl transferase-1 (CPT-1) enzyme turns the fat burning potential of the mitochondria into OVERDRIVE. You'll now the power of Mitotropin� is in full effect because as your basal metabolic rate increases and unsightly fat is being exploited in a process called thermogenesis, you will feel the furnace working from within.
Thermophoric Lypolytic Acceleration Blend
There is nothing worse than feeling run down while trying to lose weight. Let's face it, dieting can be just gut wrenching because of the hunger pangs and lack of energy from reduced calories. Mitotropin� contains a powerful combination of mood elevators and appetite suppressants to make losing fat EASY. Among them is Beta-Phenylethylamine (PEA) which is an extraordinary amine with the ability to increase dopamine release. Furthermore, PEA has also shown to regulate catecholamine levels which may quite possibly increase to mobilize stored fatty acids due to increased levels of epinephrine and norepinephrine. Quite simply, you can't burn stored fat if it's not released in the first place. Another serious issue when dieting is mental fatigue and not having the ability to focus with high degree of mental clarity. Fortunately, Gaspari researchers have solid understanding of ingredients that work backed by strong clinical research. For this reason the addition of tyrosine and huperzine A were included to round out Mitotropin� ability to limit mental fatigue during the stresses of training and attempting to burn those calories away. Maintaining cognitive integrity can ensure you are in the "zone" whether in the gym, the boardroom, or the classroom.
A lot of hard work, thought, and time went into the design and execution of this unique, amazing product by Gaspari Nutrition so that you don't have to work as hard, think as much about or waste valuable time in your quest to obtain the most shredded physique possible! Mitotropin has the power of and is protected by a United State pending patent (Pub. App. No. 20070190187). It is the only mitochondrial uncoupling agent that is both safe to use in humans and available to use in a sports nutrition product. Quite obviously, Gaspari Nutrition is recreating and redefining another category yet again in sports nutrition. This seems to happen whenever we "jump in" and offer a sports nutrition product so I am sure none of you are shocked. We expect that Mitotropin will rapidly become the "must have - go to" fat smashing/physique remodeling agent of choice not just for the upper echelon/top 1-2% crowd, but for everyone (and anyone) who demands maximum fat loss in minimum time. For some it can very well be the genetic equalizer they have long sought to bring their physiques to levels never before thought possible.
FAQ
Q: Does Mitotropin need to be stacked with any other fat burners? A: No. Mitotropin is a very powerful thermophoric mitochondrial uncoupling agent. We do formally recommend cycling it with Cytolean for longer fat reduction requirements over four weeks. The two can be cycled indefinitely.
Q: Does Mitotropin work the same way infamous mitochondrial uncouplers work like 2,4-Dinitrophenol (DNP) or Usnic Acid? A: No. Mitotropindoes not completely abolish oxidative phosphorylation nor does it generate high levels of reactive oxygen species resulting in cellular necrosis. In fact, Mitotropin increases uncoupling proteins which actually have potent antioxidant properties which may decrease oxidative stress.
Q: Is Mitotropin only for competitive bodybuilders and fitness athletes? A: No. It can be utilized by a broad spectrum of physique enthusiasts whether professionals, amateurs, or just someone wanting desperately to shed some unwanted and unsightly fat.
Q: Does Mitotropin contain ephedra? A: No. Mitotropin does not contain ephedra.
Q: Can Mitotropin be stacked with other Gaspari Nutrition products? A: Yes. It is stackable with every product in the line with exception of Cytolean V2. However, you can cycle between Mitotropin� and Cytolean V2 for optimal fat loss over long durations of time.
Yes, we have a brand new product like you just read in the headline! I am very excited to tell you about it and I am 100% sure that after you read this, you're going to insist on trying this product. Literally, if you want to incinerate slabs of fat as fast as humanly (and legally) possibly then Mitotropin is going to be your "must have - go to" product. I'm sure of it! The more astute of you will probably realize that Gaspari Nutrition already has an exceptional weight loss product and we plan on continuing to sell that product. It's called Cytolean and like all Gaspari Nutrition products, it works better "doing what it is supposed to do" than just about anything else in the sports nutrition marker. Cytolean absolutely crushes your appetite. We were the first company to manufacture and market a commercially viable weight loss/appetite reducing product using a biogenic amine, phenylethylamine (PEA) and a monoamine oxidase inhibitor (MAOi) with our Cytolean product. We have a pending patent regarding our ground breaking use of PEA and MAOi (Pub. App. No. 20070190187). This has not stopped some of our "less than ethical" competitors whose research and development consists merely of scanning the ingredients panel of Gaspari Nutrition labels. You know who you are! One such company, I won't mention any names, went even farther than just copying Cytolean, they actually lifted/plagiarized the entire Chemical Corner piece on Cytolean. Maybe we should send them a bill for doing their formulating as well as marketing work now? You'd think we'd be used to this kind of stuff by now. I am equally sure these guys - and countless other companies - will try to copy the innovative, revolutionary approach we are taking here with Mitotropin, but just remember, it won't be Mitotropin and it won't work like Mitotropin. So remember where you saw it first and which company brought the concept to you. Gaspari Nutrition: We always bring it to you first and we always bring it to you right! So to all the companies who are about to knock this product off, we say, "You're Welcome! Again! -and good luck with that!"
If you have followed any of the previous Chemical Corners, you would know that while our team of formulators puts up with me for the most part, they sometimes get a little "cranky" when I set the proverbial "bar too high" for developing new products. So when I asked them to formulate a new fat smashing product that utterly lays waste to adipose tissue and is leagues better than anything our competitors could ever possibly dream of doing - and these in fact were my exact words from the original email, "I want to see a product that actually kills anything else out there in the fat loss area, not just better than anything else, it has to be so powerful that it makes the other stuff look like it doesn't work at all! Guys, you need to make sure Mitotropin is the complete package in fat loss!" - I knew the team was in serious trouble from a formulational perspective. In regard to fat loss, I have a pretty good idea what it takes to be a champion in that "top 1%." If I was going to stick the company's neck out and claim victory here, it would have to be with a product that would absolutely take you there.
Using the traditional list of "caffeine, yohimbine, capsicum, etc.," in insane dosages like all the other "copycat" companies typically wouldn't cut it because our formulators wouldn't be fooling our more difficult and critical customer - ME! This time, they would have to take a page out of the professional bodybuilder's manual, open the proverbial "black box" of secret tricks said people use to look "upper echelon/top 1-2%". Serious times call for serious measure. They decided to use something called a mitochondrial uncoupling agent (MUA) and although I'm pretty familiar with them, boy did I get a lesson here. Essentially, these disrupt the linkage between the respitorary chain and phosphorlyation system in mitochondria. By doing so thermogenesis is increased greatly as ATP synthesis decreases within the mitochondria as the proton gradient diminishes. This happens naturally in hibernating mammals who must maintain a constant body temperature in temperate environments (J Appl Physiol. 2006 Jul;101(1):339-47. MUA's have a very checkered past in our industry. Nothing works like them from a biochemical standpoint or as well as them from observable fat reduction. They take the fat off and they do it with mind boggling speed. The first MUA to rear its head in our industry came from the bag of dieting tricks of our chief formulator's late mentor, "The Guru" Dan Duchaine. I am talking about DNP (2,4 - dinitrophenol), a substance the chief did countless hours of research on as Duchaine's right hand man/research assistant. Those "in the know" called DNP "Dieting By Bug Spray" or "Orange Death" and for good reasons. Used judicially and intelligently, nothing works as well or as fast as the orangey-yellow colored powder which is DNP. Used irresponsibly and haphazardly and DNP would literally cook you from the inside out -a handy fact used by pesticide companies years ago (it cooked bugs dead if they ingested too much DNP). Still, despite the absurd risks associated with its use, DNP became an indispensable part of the regiment that many upper tier bodybuilders secretly used before a contest. Blow your diet? No problem, just take a little DNP. Not doing enough cardio? DNP can fix that and you will still lose the fat. Most of you know that DNP is absolutely illegal to sell or use for human consumption! Usnic Acid/Sodium Usnate was the next MUA to appear in our industry. This compound is extracted from a lichen (which coincidentally, has evolved to use this compound to keep competitors from munching on it - a built-in "predatoricide!") and it worked very well with regard to fat loss. Duchaine had his fingers in on this one too and some of you "old timers" will remember that Dan and the Chief (we'll call him "Mr.B.") had serious disagreements over the use of this stuff - Mr. B had warned everyone and anyone who would listen that this stuff was way too dangerous for use in our industry. It cleaved fat right from your body. Some people went so far as to proclaim it "chemical exercise in a bottle." But Usnic Acid/ Sodium Usnate was horribly carcinogenic and it "broke" chromosomes inside the cells causing permanent genetic damage. It has been linked to a substantial number of deaths as well as complete and total liver failure requiring organ transplants. The FDA issued a serious warning letter regarding the use of this stuff (FDA Consum. 2002 Mar-Apr; 36(2):4.) and it too, is not found in our realm anymore. So what the team needed to find was a safe MUA if possible, something that offered all the fat frying benefits without the nasty side effects of the previous two. Mr. B. failed in this task. He did not find one. But somebody else (a Gaspari employee!) did luckily. Some of you might know him as our internet representative and we know him as our crack research assistant. For the purposes of this piece we will call him "Mr. D." (Hey this is really starting to sound sinister….I like it!) He spends countless hours blogging and advising bodybuilders and fitness enthusiasts online at Bodybuilding.com and other sites when he's not buried neck deep reading the latest breaking clinical research studies. He is a valuable asset to GN and we have Mr. B. to thank for bringing him on. So let me tell you a little story about "D." When B first approached D with this project, D said a bit humbled. "Gaspari is known for its world class products and better yet, one of my bodybuilding heroes growing up was now seeking an important solution from me!" Talk about pressure. You must know that D has his nose in everything when it comes to published research; however this was a daunting task. A safe and effective mitochondrial uncoupler? HA! Off to the library went D. Fortunately for him, he has some pretty amazing resources at his disposal but he really didn't know where to begin. According to D, "Traditional MUA's are unsafe just because they are dose dependant and the slightest error meant you couldn't turn off the effects and essentially roasted yourself. Not good." Staring at thousands of volumes of medical texts muttering to himself, "Safe mitochondrial uncoupler, safe mitochondrial uncoupler." All of the sudden D remembered a concept he learned when researching how hibernating mammals stay warm despite inactivity: Increased mitochondrial uncoupling proteins (Genome Biol. 2002; 3(12): REVIEWS3015). So where did that leave D? "I needed to find the right combo of ingredients that could gently increase uncoupling proteins to crank up REAL FAT BURNING which any competitor could appreciate and effectively incorporate into their arsenals without question."
FUCOXANTHIN
First and foremost D began his industry journey as an educated consumer sitting on the sidelines only a few years. He read everything regarding supplements he could get a hold of and luckily recalled an interview with industry author Anthony Roberts (http://blog.anthonyrobertsonline.com) a few years back in which he mentioned a seaweed extract called fucoxanthin. Said D, "This brown seaweed extract increased UCP1 levels in white adipose tissue (WAT) which was supported by some compelling clinical research (Biochem Biophys Res Commun. 2005 Jul 1; 332(2):392-7.). It appeared that I had the first piece of a complex puzzle in increasing uncoupling protein expression to crank up the rate of fatty acid oxidation in mitochondria. WAT is found in the belly region (aka spare tire, paunch) so who wouldn't mind taking a perfectly safe compound to get rid of it?"
3'-DIIODOTHYRONINE AND 3,5-DIIODOTHYRONINE
There is no doubt that if you have ever considered bodybuilding that you are aware of what T3 is. Sure, it works like a charm for throwing your metabolic rate through the roof but it's absolutely illegal. However, what about its first order metabolites? This is where 3,3'-diiodothyronine and 3,5-diiodothyronine come in to the picture which are more commonly referred to as 3,3'-T2 and 3,5-T2. Both of these metabolically active compounds have been shown to raise resting metabolic rate (RMR) (Thyroid. 2008 Feb; 18(2):239-53. Review.). However, a common misconception is that iodothyronines only have activity in the thyroid. Very rarely is their activity in the mitochondria of skeletal muscle, the liver (where hepatic fatty acid oxidation takes place, adipose tissue discussed yet this is where they can truly be targeted for effective fat burning. 3,3'-T2 declines with age which may be attributed to age related declines in metabolic rate. It may very well have the transient ability to increase caloric expenditure thereby increasing RMR (Am J Physiol. 1956 Jul; 186(1):1-5). 3,5-T2 on the other hand, has its effect on RMR by increasing fatty acid oxidation rates in the liver and by stimulating the CPT (carnitine-palmitoyl-transferase) system of the mitochondria. Furthermore, it also has the ability to increase uncoupling proteins and uncouple oxidation substrates in the mitochondria. This is key because if fatty acids can't cross through mitochondrial membranes effectively fat loss then becomes a distant dream. This is where Mitotropin truly shines.
This is a polyphenolic ingredient found in numerous edible plant species. It has the ability to increase energy expenditure and oxygen consumption via multiple pathways (dia. 2007 Mar; 56(3):767-76.). The most prevalence pathway manipulated was Dio2 expression. This gene is important in encoding the type 2 deiodinase (D2) that activates thyroxine (T4) to 3,3?,5 triiodothyronine (T3). Now some of you are thinking that increased T3 levels aren't a good thing, but maybe those of you that are "hardcore" know it certainly doesn't impair fat loss. In fact, T3 has been shown to UCP-3 expression in vivo which directly correlates with resting metabolic rate. Basically, if your levels are low, you aren't burning as many calories at rest then not. It's clear to me that keeping them optimal keeps you chances at maintaining a streamlined appearance very high.
CAPSIATE
Have you ever eaten a red pepper and noticed that it made you feel hot? Perhaps you were distracted by the fact your mouth felt as if it were on fire? Well peppers contain substances called capsinoids. These are responsible for the "hotness" associated with their ingestion. Capsiate is rather unique because it has shown to increase UCP 1 & 3 all the while not having the tongue and eye blistering effect of its cousin capsaicin (found in pepper spray). Moreover, it also may potentially have a strong effect as a vanilloid receptor agonist (TRPV1) along with evodiamine to provide extremely effective adrenaline secretion and the reduction of fat accumulation by burning more calories.
When the day came to finally beta test this product, the results after 30 days were stone cold unbelievable! One of our top guinea pigs, Gaspari resident (and new) IFBB pro James "Flex" Lewis was both kind and brave enough to run the Mitotropin "kit" for the full 30 days leading into the Europa Supershow in Dallas. As history would have it, he absolutely crushed the field in the 202 class to claim his first professional victory at the age of 24. And let me tell you - it was all about the conditioning! The kid was beyond shredded. With striated glutes and all, I felt like a proud papa as I watched him capture the day. I am absolutely sure that with MITOTROPIN, Gaspari Nutrition is recreating and redefining yet another category in sports nutrition.
Rich Gaspari knows bodybuilding and what it takes to be successful in bodybuilding. And Rich wants to really help you in becoming a successful bodybuilder or fitness enthusiast too!
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